Which statement describes Targeted Muscle Reinnervation (TMR)?

• A. It connects nerves from an amputated limb to remaining unused muscles, which then act as biological amplifiers for prosthetic control
• B. It uses EMG signals from the intact limb to move the prosthesis
• C. It is a training protocol that rewires brain circuits
• D. It is a mechanical device to adjust socket fit

Answer: (A)

Targeted Muscle Reinnervation involves surgically rerouting nerves that used to control the amputated part to remaining, unused muscles. These muscles then act as biological amplifiers: when the reinnervated nerves fire, the muscles generate EMG signals that reliably reflect the intended movement. The prosthetic controller decodes these signals to produce intuitive, multi-degree-of-freedom control of the limb. This is different from using signals from the intact limb, which would rely on the opposite side; it’s not a brain-training protocol, and it’s not a device to adjust socket fit.