What happens in diaschisis in the brain?

• A. Permanent loss of function in remote areas.
• B. The recovery of function in areas of the brain that were previously inhibited due to a distant primary lesion.
• C. Growth of new neurons at the lesion site.
• D. The development of new neurological pathways for every task.

Answer: (B)

Diaschisis is a temporary drop in function in brain regions that are distant from a focal lesion, caused by disrupted connections and reduced input from the damaged area. Because those remote areas lose excitatory drive and altered metabolic signaling, their activity decreases. As the brain heals and networks re-balance, function in these areas can recover, so you see improvement in regions that were previously inhibited by the distant lesion. This is not about permanent loss, nor about growth of new neurons at the lesion site, nor about creating new pathways for every task.